Intrapopulation variability in mineralization density at the human femoral mid-shaft

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Intrapopulation variability in mineralization density at the human femoral mid-shaft.

One of several microstructural variables known to affect the mechanical properties of bone is the degree of mineralization of bone matrix. The aim of this study was to examine mineralization density, and its variability with age and sex, from a biomechanical perspective. Histological sections, prepared from mid-shaft femora obtained at autopsy from 40 individuals, were imaged using quantitative...

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Collagen fiber orientation is one aspect of the microstructure of bone that influences its mechanical properties. While the spatial distribution of preferentially oriented collagen is hypothesized to reflect the effects of loading during the process of aging, its variability in a modern human sample is essentially unknown. In a large sample (n = 67) of autopsied adults, the variability of colla...

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Femoral shaft fractures in children.

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Ontogenetic patterning of cortical bone microstructure and geometry at the human mid-shaft femur.

The bone growth process has long-lasting effects on adult bone structure and mechanical adaptation, yet the tissue level dynamics of growth are poorly studied. The specific aims of this study were to (1) quantify changes in bone size and shape through ontogeny, (2) describe the distribution of tissue types and patterns of cortical drift and expansion through ontogeny, and (3) explore relationsh...

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ژورنال

عنوان ژورنال: Journal of Anatomy

سال: 2003

ISSN: 0021-8782,1469-7580

DOI: 10.1046/j.1469-7580.2003.00212.x